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Sleeping pills make you unconscious, not asleep. They impair the sleep cycle. They increase dementia, falls, and death. And they're highly addictive.

Sleeping pills deprive people of true sleep and they impede essential brain functions (which are causes of dementia, Alzheimer’s and other neurodegenerative diseases)

Shelly Thorn's avatar
Shelly Thorn
May 02, 2025
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For many, sleeping pills seem like the easiest solution… While these drugs offer a quick fix, the reality is that they force your brain into a sedated state that looks nothing like natural sleep. They may make you unconscious, but they don’t allow the brain to go through its essential cycles of repair and detoxification. A recent study published in the journal Cell revealed… how sleeping pills disrupt the synchronized oscillations that drive the brain’s glymphatic system, which clears waste linked to neurodegenerative diseases.

Dr. Joseph Mercola

Contents

  1. Context: Pharmaceutical Drug Harms

  2. Sleeping Pills, Sedatives

  3. Evidence of Harm

  4. Evidence-Based Therapies for Consideration

  5. For Wellness Providers & Educators: Boost Your Impact — Premium Resources Just a Click Away from $19

  6. See Also

Context: Pharmaceutical Drug Harms

  1. Pharmaceuticals generally + overprescription — In a controlled trial with disabled elderly adults, doing nothing except terminating some of their prescriptions dropped the death rate by 53% compared to the control. “More than half of the patients were candidates for deprescribing. The most common criterion was inappropriately long use, followed by safety concerns, and lack of indication.”

  2. Acid blockers, PPIs, drugs for acid reflux, heartburn, GERD, gastric ulcer — PPIs increased cancer, heart disease, osteoporosis and bone fractures, chronic kidney disease, neurodegeneration including Alzheimer’s and dementia, all-cause mortality (death), B-12 deficiency, pneumonia, and infections. PPIs altered children’s gut microbiome, the foundation of immunity and health, and increased infections in children. Stomach acid is crucial for health.

  3. ADHD drugs, stimulants —Caused “long-lasting changes” in brain function “similar to those that occur with cocaine.” “There is no such thing as a Ritalin deficiency.” Harms from ADHD drugs are many, and effects from higher doses are severe. Get verifiable research and alternatives for resolving the underlying issues.

  4. Alzheimer’s, dementia, and Parkinson’s drugs — Alzheimer’s & dementia drugs are less effective than B vitamins. And they cause fluid build-up & bleeding in the brain and increased death. Parkinson’s drugs deplete nutrients needed for brain health. Parkinson’s symptoms can be reversed. Successful therapies promote brain autophagy, “the removal of old and damaged brain cells and the creation of new and healthy brain cells.”

  5. Antibiotics — “Like TNT for the body’s microbiome” and linked with kidney stones, infertility, miscarriage, birth defects. Since 70 to 80% of the immune system is in the gut, damage to gut health is damage to immune health. Review curated research + alternatives and considerations.

  6. Asthma, allergy & hay fever drugs, antihistamines — Antihistamines cause heart problems, cognitive impairment, seizures in kids. Asthma “med” caused depression, anxiety, aggression, suicides. “Common medications like diphenhydramine [called benadryl, other brand names] cross the blood-brain barrier, disrupting normal brain activity and lowering seizure thresholds in vulnerable children.”

  7. Blood pressure drugs — Allergies, Diabetes, Weight Gain, Sexual Dysfunction, Depression, Acute Kidney Injury, Lung Cancer, Abnormal Heart Rate, and More. Blood pressure-lowering drugs have not been shown to be effective; do not address the root cause(s) of hypertension; have been contaminated with cancer-causing agents; and cause harm (“side effects”).

  8. Chemotherapy, other cancer drugs, radiation — “Chemotherapy makes cancer worse.” “Chemotherapy doubled the number of cancer cells in the bloodstream and lungs.” “Omitting radiation from treatment did not have an effect on survival rates.” “Radiation therapy increases the risk of solid tumors.” Chemotherapy drugs harm the healthcare professionals who administer them.

  9. Diabetes drugs, metformin — Caused death, low blood pressure, slowed heart rate, reduced blood flow to brain & organs. 90% + of diabetes is reversible with diet but professionals push drugs that harm. Professionals avoid telling the simple truth about the effectiveness of low carb diets and push profitable drugs that cause harm. In 2023, the FDA approved more drugs to treat diabetes in children.

  10. Osteoporosis drugs, bisphosphonates — Caused “substantially reduced bone strength” and caused more microcracks in bone than the controls. Osteoporosis drugs caused blood calcium levels to drop, digestion problems, internal bleeding, irregular heartbeat, bone fractures, and bone death.

  11. Over the counter drugs (OTCs) — Tylenol: ADHD, autism, ulcers, GI issues, kidney disease, heart failure. Laxative given to children: rage, tics, insomnia, seizures. Ibuprofen: DNA damage, hypertension. Sunscreens? Nightmare. Prescription drugs cause great harm, but so do over-the-counter meds and personal care products. Get an organized curation of research and reports.

  12. Pain relievers, NSAIDs, opioids — Even at “safe doses,” opioids cause confusion, dependence, depression, increased pain sensitivity, diminished energy, and low sex drive. Consistent use of NSAIDs caused heart attacks. Doctors are not trained in pain management or addiction, but they prescribe dangerous, highly addictive drugs. Get an organized curation of research and reports, plus alternatives and considerations.

  13. Psychiatric drugs: antidepressants, SSRIs, anti-anxiety, benzos, other psychotropics — Anti-depressants cause suicidal thinking, violence, and homicide. Anti-anxiety drugs cause insomnia and anxiety. Anti-psychotic drugs cause agitation, psychosis and violence. This organized curation of research and reports makes it clear that the evidence of harm from psychotropic drugs is overwhelming. We also provide alternatives and considerations.

  14. Scans, radiology, & ultrasounds (e.g. mammograms, CT scans, X-rays) — Medical scans (CT scans, mammograms, etc) use ionizing radiation which damages DNA and causes cancer. Research and resource curation, including research showing that 1) mammograms do not reduce risk of death, and 2) a higher incidence of breast cancer was caused from mammography radiation.

  15. Seizure drugs, anticonvulsants, anti-epileptic drugs (AEDs) — Devastating effects, negatively impacting virtually every system of the body, including damage to blood vessels and reduction in all three types of blood cells. Seizure drugs caused liver failure and death in young people and in healthy adults. A long list of non-harming alternatives listed below, with links to research on their effectiveness.

  16. Sleeping pills, sedatives (you’re here) — Sleeping pills make you unconscious, not asleep. They impair the sleep cycle. They increase dementia, falls, and death. And they’re highly addictive. Sleeping pills deprive people of true sleep and they impede essential brain functions (which are causes of dementia, Alzheimer’s and other neurodegenerative diseases)

  17. Statins — Statin drugs damage health at foundational levels — mitochondria, muscles and nerves — which can lead to more than 300 health problems. Research curation on statin harms, plus research showing that 1) lowering cholesterol does not improve heart health, and 2) statins do not lower all-cause death rates.

  18. Steroids — Cause osteoporosis and double the risk of bone fractures. They increase heart failure, diabetes, psychiatric issues, glaucoma, and serious infections. Steroid users report rapid weight gain, intense hunger, irritability, anxiety, depression, sleep problems, acne, stomach pain, nausea, joint pain, and withdrawal reactions, among other adverse events.

  19. Vaccines — Reports by vaccine type.

  20. Weight loss drugs — Ozempic & Similar Weight Loss Drugs Cause Kidney Failure, Pancreatitis, Thyroid Cancer, Gallbladder Issues, Depression, Severe Stomach Problems, Bone & Muscle Loss, Blindness, and Death. “Ozempic, similar weight loss drugs linked to 162 deaths in U.S.” Get an organized curation of research and reports, with quick links to verify sources.

Sleeping Pills, Sedatives

  • Sleep drugs include Ambien, Anxiolytics, Belsomra, Benzodiazepines, Hypnotics, Suvorexant, Tranquilizers, Z-Drugs, Zaleplon, Zolpidem, and Zopiclone. [source and source]

  • This section focuses on sleeping pills generally. Get much more detail on the harms from benzodiazepines here.

Sleeping pills and minor tranquillisers are sedative medications. This means they slow down your body and brain’s functions. For example, this may be your breathing, heartbeat and thought processes. These medications can be prescribed for severe anxiety or insomnia (difficulty getting to sleep or staying asleep). This includes prescribing: benzodiazepines [and] non-benzodiazepine sleeping pills. You may also hear these drugs referred to as hypnotics and anxiolytics. Although we use the term ‘sleeping pills’ to describe many of these drugs, some of them may also be available as a liquid, either to swallow or inject…

Take sleeping pills for no longer than three weeks, ideally no longer than a week… Avoid taking them every day.

Mind

Evidence of Harm

  1. Sleeping Pills Impair the Sleep Cycle and the Brain’s Ability to Detoxify, which are Root Causes of Dementia and Alzheimer’s — “The sleep aid zolpidem suppresses norepinephrine oscillations and glymphatic flow.” See also: How Sleeping Pills Harm Your Brain and Raise Dementia Risk: “Your brain has a cleaning mechanism called the glymphatic system, which flushes out harmful toxins during deep sleep, including beta-amyloids and tau proteins linked to neurodegeneration. A 2025 study found sleeping pills suppress norepinephrine oscillations. This impairs the glymphatic system’s waste removal function and causes toxin buildup in the brain. Sleeping pills increase risks of falls, car accidents and workplace injuries. Long-term use is also linked to higher mortality, cancer risk and cognitive decline. Instead of taking sleeping pills, address the root cause of your sleeplessness through the strategies outlined below.” See also: Common Sleeping Pill Potentially Linked to Alzheimer’s, Other Disorders, Study Finds; “A common sleeping medication, zolpidem, commonly known by the brand name Ambien, may disrupt the brain’s ability to ‘cleanse’ itself during sleep, potentially raising the risk of Alzheimer’s and other neurological disorders.” See also: Common sleep medication may prevent brain from clearing ‘waste’ See also: Insomnia: War on Sleep; “Studies have shown that disrupted sleep causes an accelerated accumulation of Alzheimer’s plaques in the brain and can forecast the development of dementia. Deep sleep has been shown to mitigate the cognitive impairment created by Alzheimer’s plaques. [See more: Alzheimer’s – Lies are Unbekoming]

  2. People Using Sleeping Pills Were Far More Likely to Die — “Receiving hypnotic prescriptions was associated with greater than threefold increased hazards of death even when prescribed <18 pills/year… Estimates… suggest that in 2010, hypnotics may have been associated with 320 000 to 507 000 excess deaths in the USA alone.” See also: Use of Sleep Medications and Mortality: The Hordaland Health Study; “Sleep medication use [was] associated with increased [death]. Compared with participants not using sleep medications, those who reported any use had a twofold risk for mortality… The hazard ratio was 2.9 for daily users.”

  3. Sleeping Pills are Highly Addictive

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