PPIs, heartburn, acid reflux, GERD drugs: Increase cancer, heart disease, kidney disease, dementia, death, bone fractures, vitamin deficiency, pneumonia and infections.

PPIs altered children’s gut microbiome, the foundation of immunity & health, and increased infections in children. Stomach acid is crucial for health.

10 min, PPIs increase cancer, heart disease, osteoporosis, chronic kidney disease, neurodegeneration including Alzheimer’s and dementia, and all-cause mortality (death).

Sold both by prescription and over the counter... proton pump inhibitors (PPIs) have been linked to numerous severe side effects: chronic kidney disease, kidney failure, heart attacks, pneumonia, dementia, bone fractures, and vitamin and mineral deficiencies. Patients have even begun to file lawsuits, claiming the companies behind these blockbuster drugs were aware of the risks but failed to warn the public.

Dr. David Jockers

Contents

1. PPIs, Heartburn, Acid Reflux, GERD, Gastric Ulcer Drugs

2. Evidence of Harm

3. Context: See how this subject fits in the bigger picture, and get links to related topics

PPIs, Heartburn, Acid Reflux, GERD, Gastric Ulcer Drugs

The following prescription and over-the-counter drugs are used for heartburn, indigestion, acid reflux, GERD (gastro-oesophageal reflux disease) and gastric ulcer.

• Antacids are OTC (over the counter) and include Aluminum Hydroxide, Calcium Carbonate, Gaviscon, Magnesium Trisilicate, Mylanta, and Tums. [source]

• H2 Blockers/Antagonists (histamine type 2 receptor antagonists) are OTC (over the counter) and include Axid, Cimetidine, Famotidine, Fluxid, Nizatidine, Pepcid, Ranitidine*, Tagamet, and Zantac*. [source and source]

• PPIs (proton pump inhibitors) include Aciphex, Dexilant, Dexlansoprazole, Esomeprazole, lansoprazole, Lansoprazole, Nexium, Omeprazole, Pantoprazole, Prevacid, Prilosec, Protonix, Rabeprazole, and Zegerid. [source and source]

• Promotility Agents include Bethanechol, Cisapride, Domperidone, Metoclopramide, and Metozolv. [source]

*Ranitidine [Zantac] was “revoked from the market in 2020 because it contained cancer-causing agents.” [source and source]

Evidence of Harm

1. PPIs: Increased Cancer, Heart Disease, Osteoporosis, Chronic Kidney Disease, Neurodegeneration including Alzheimer’s and Dementia, All Cause Mortality (Death), Bone Fractures, B-12 Deficiency, Pneumonia & Infections — “Sold both by prescription and over the counter... proton pump inhibitors (PPIs) have been linked to numerous severe side effects: chronic kidney disease, kidney failure, heart attacks, pneumonia, dementia, bone fractures, and vitamin and mineral deficiencies. Patients have even begun to file lawsuits, claiming the companies behind these blockbuster drugs were aware of the risks but failed to warn the public.” See also: Proton pump inhibitor utilisation and potentially inappropriate prescribing analysis: insights from a single-centred retrospective study: “PPIs have… been associated with a variety of severe adverse effects such as osteoporosis and associated fractures, hypomagnesemia… pneumonia, Clostridium difficile colitis and cardiovascular morbidity.” See also: Long-Term Use of Popular Heartburn Drugs Increases Risk of Stomach Cancer: Review See also: Several Common Drugs Are Linked to Dementia: “PPIs… have been shown in studies to increase people’s risks of dementia by 44 percent.” See also: This Pill Causes Dementia (14-min video) See also: These 7 Common Everyday Meds Are Harming Your Kidneys (13-min video) See also: 5 Common Medications that can Trigger Autoimmune Disease (video) See also: Vitamin B₁₂ in Health and Disease: “Some medications are thought to interfere with the absorption or metabolism of vitamin B₁₂. These include proton pump inhibitor (PPI) medications, metformin, nitrous oxide anaesthesia, some epileptic medications and colchicine.” See also: Warning Signs of a B12 Deficiency

2. PPIs Altered Children’s Gut Microbiome, the Foundation of Immunity & Health, and Increased GI and Respiratory Infections in Children — “PPI use increases the presence of oral microbes in the stool. We measured this microbial alteration in most pediatric subjects and observed that younger children are more susceptible to the PPI-associated microbial shifts. Our data suggest that PPIs drive a mixing of the microbial populations in the upper and lower GI tracts, which may explain a mechanism by which PPIs put children at risk for a myriad of GI and non-GI diseases.” See also: New insight into the effects of proton-pump inhibitors in children: “Prescribing rates of PPIs in children have risen more than 500% in the past two decades, despite growing concerns about their risks. Previous research has linked their use to an increased risk of various pulmonary and gastrointestinal infections in both adults and children.”

3. Stomach Acid is Crucial for Health — “Stomach acid is crucial for health, performing vital functions like protein digestion, nutrient absorption, and pathogen elimination.” See also: Stomach Acid is Good for You: The many dangers of acid blocking medications: “Many pharmaceuticals on the market are automatically given to large numbers of patients despite the harms often greatly outweighing their benefits. One of the worst offenders is acid suppressing medications. Their overprescription goes hand in hand with a widespread medical blindness to the critical functions of hydrochloric acid throughout the body and the actual causes of acid reflux. A variety of safe and non-invasive approaches exist to address the wide range of (often unrecognized) complications from acid reflux and dysfunctional stomach acid production.” See also: Stomach Acid is Critical for Health

Over 90% of Patients Have Too Little Stomach Acid, Not Too Much. When Sufficient Acid is Not Present, the Esophageal Sphincter Doesn’t Close Properly.

Over 90% of patients tested had low stomach acid levels, contrary to common medical assumptions. Proton Pump Inhibitors (PPIs) are overused and can be harmful. 15% of the US population takes PPIs, with usage increasing with age. Long-term PPI use is associated with [an] increase in overall death risk. Acid reflux is often caused by too little stomach acid, not too much. The lower esophageal sphincter (LES) closes properly only when sufficient stomach acid is present… Low stomach acid is linked to various autoimmune conditions. In one study, over 80% of asthmatic children had below-normal acid secretion. PPIs can increase the risk of infections. Ventilated patients on acid-blocking medications were twice as likely to develop pneumonia and 60% more likely to die from hospital-acquired pneumonia. Nutrient absorption is impaired by low stomach acid. For instance, calcium absorption increased five-fold when stomach pH was lowered from 6.5 to 1 in one study. H. pylori infection, present in about 50% of the world’s population, can decrease stomach acid production and is associated with an increased risk of stomach cancer... Natural approaches like betaine HCl supplementation, bitters, and lifestyle changes can effectively manage acid reflux for many people. Wright reported that over 50% of asthmatic children he treated were cured by normalizing stomach acid and administering vitamin B12. Overprescription of medications significantly affects elderly patients. One study found that discontinuing unnecessary medications in nursing home residents reduced the death rate by 23% and hospital referrals by 18.2%.

Lies are Unbekoming

Context, Organized Curation

This article is a subset of a vast resource curation on the failure and corruption of establishment medicine. See here for the entire curation, or select links below to focus on an individual subject.

The subject matter above is an excerpt from Harms by Drug or Test.

1. Failed Health Outcomes — The U.S. spends nearly twice the per-capita amount on healthcare than the next highest spender, yet Americans are the most chronically ill, and rank 48th in life expectancy, among other countries. In addition, medical misdiagnosis causes permanent harm and death to 795,000 people every year.

2. Verifiably Corrupt — Establishment medicine as a system* is verifiably corrupt, serving the interests of industry — not health. (*Obviously, not every individual working in establishment medicine is unethical. Rather, the system that educated / indoctrinated them, and that sets policy, hires, pays, and promotes them is verifiably corrupted.)

3. Big Pharma & Biotech: Immoral Business Model — Corporations, by design, are beholden to profit above all else, acting as powerful entities that are “essentially psychopathic and without conscience.” Pharmaceutical and biotech companies are the utmost example of corporate psychopathy, demonstrating inhumanity in response to human suffering.

4. Regulatory & Professional Betrayal — Government agencies entrusted to regulate the field of medicine fail to do so. The majority of influential professional organizations such as the American Medical Association are corrupted by industry.

5. Not Evidence/Science-Based — The bulk of establishment medicine’s standard of care is not backed by unbiased, reproducible science. (We prove it here.)

6. Harms, by Drug & Diagnostic — Establishment medicine providers routinely utilize diagnostic testing and “treatments” that cause harm (“adverse”, “side” effects). Get verifiable evidence of the harms, organized by drug and diagnostic test (e.g. antibiotics, PPIs, CT scans, and so on).

7. Failed Strategies & Procedures — The philosophies, strategies, and procedures used by establishment medicine are dysfunctional and irrational, including a focus on suppressing symptoms rather than understanding them. Providers do not seek to identify and resolve the root causes of illness, and diagnosis is simply an exercise in naming groupings of symptoms, disconnected from their purpose and message.

8. Root Causes of Illness — With knowledge of causal factors, true healing is possible. Quickly identify drugs, vaccines, toxins, and nutrient deficiencies that cause illnesses and symptoms e.g. depression, infertility, kidney issues, cancer, seizure, etc. Quickly verify documented “side effects” and evidence of harm.

9. Stifling Treatments That Don’t Enrich Industry — Healing modalities that don’t benefit industry are underutilized, suppressed, and disparaged. Providers who are perceived as a threat to establishment dictates or lucrative markets are condemned, intimidated and attacked.

10. Suppressed Cancer Treatments — Cancer treatments that don’t benefit establishment medicine are ignored and disparaged. This curation of more than 150 clinical studies and testimonials provides quick access to documented cancer reversal and recovery successes.

11. The Significance of Legal Precedent — Legal precedent, breach of duty, and “standard of care” are significant factors in the state of the medical industry.

12. Alternatives & Considerations — Alternatives, considerations, and what you can do.